8/27/2023 0 Comments Download cholecalciferol useHow to optimize vitamin D supplementation to prevent cancer, based on cellular adaptation and hydroxylase enzymology. The case against ergocalciferol (vitamin D2) as a vitamin supplement. supplementation with vitamin D2 or D3 on serum 25-hydroxyvitamin D metabolites: an 8-week randomised-controlled trial in young adult Finnish women. Itkonen ST, Skaffari E, Saaristo P, Saarnio EM, Erkkola M, Jakobsen J, et al. Vitamin D supplementation for prevention of mortality in adults. 2012 95:1357–64.ījelakovic G, Gluud LL, Nikolova D, Whitfield K, Wetterslev J, Simonetti RG et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. Tripkovic L, Lambert H, Hart K, Smith CP, Bucca G, Penson S, et al. Baltimore, MD, USA: Lippincott Williams & Wilkins 2005. Stedman’s Medical Dictionary for the Health Professions and Nursing. Why ‘Vitamin D’ is not a hormone, and not a synonym for 1,25-dihydroxy-vitamin D, its analogs or deltanoids. Therefore, it must be concluded that cholecalciferol is the only form of vitamin D that should be considered in the context of the nutritional functions of fortification and supplementation. Recent evidence shows that ergocalciferol is not stable with storage, and it is far more susceptible to breakdown with cooking and baking than is cholecalciferol. Nutrition policy papers and guidelines leave unstated the obvious fact that calcidiol and calcitriol are not nutrients, and that those metabolites are not pertinent to food fortification or dietary supplementation. Calcidol is the major circulating metabolite of cholecalciferol, while calcitriol is the hormone that upregulates the active transport of calcium from the gut, and which suppresses parathyroid hormone secretion. ![]() ![]() In contrast, ergocalciferol is primarily a synthetic and less stable product which is less potent per microgram dose than is cholecalciferol. In nature, by far the major form of vitamin D that nurtures the body is cholecalciferol. The term “supplementation” has been used in the context of cholecalciferol, ergocalciferol, calcidiol, and calcitriol. The specific compound that is meant for use in the context of vitamin D supplementation is often ambiguous.
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